Stability studies typically involve long-term, accelerated, and intermediate testing. Long-term studies provide information about the API’s stability under normal storage conditions, often conducted over a period of 12 months or more. Accelerated testing involves higher temperatures and humidity levels to expedite decomposition, allowing manufacturers to predict long-term stability in a shorter time frame. Intermediate testing often serves as a bridge, assessing stability under conditions that fall between long-term and accelerated studies.
In addition to supporting mitochondrial health and cognitive function, PQQ has also been studied for its potential role in heart health. Some animal studies have shown that PQQ can reduce the risk of heart damage after ischemic events, such as a heart attack. It may also help lower blood pressure and improve lipid profiles by reducing levels of harmful LDL cholesterol. These cardiovascular benefits highlight the nutrient's potential as a key player in preventing one of the leading causes of death worldwide.
Moreover, sustainability has become a critical factor in procurement strategies. Buyers are increasingly tasked with considering the environmental impact of their sourcing decisions. This includes evaluating suppliers' sustainability practices and looking for ways to minimize waste and reduce carbon footprints throughout the supply chain.
The pharmaceutical industry has seen significant advancements in technology that enhance the development of APIs. This includes high-throughput screening, improved synthesis techniques, and sophisticated biological assays that facilitate a better understanding of how these substances interact within the body.